A recent study by researchers from the Perlman School of Medicine at the University of Pennsylvania revealed a strong link between disrupted biological rhythms, excess weight gain, and an increased risk of developing diabetes. The research showed that people who work night shifts or have irregular eating schedules are more prone to these health problems. The primary reason for this is the disruption of the natural biological rhythm of the organism. The liver has its own "biological clock," which sends signals to the brain for determining the optimal timing of food intake.
When this rhythm is disrupted, as can happen in cases of night work, the brain compensates for it with increased appetite and food consumption at inappropriate times, leading to excess weight gain and a higher risk of diabetes. The researchers focused on genes called "REV-ERBs," which are found in liver cells and play a vital role in regulating daily rhythms. Experiments on mice showed that blocking these genes leads to increased food intake at inappropriate times. The researchers also discovered that interrupting the neural connection between the liver and the brain results in a restoration of the natural feeding pattern and a reduction of unnecessary consumption. This is an effective method for treating disrupted feeding patterns related to biological rhythm disruptions.
